|
Laboratorio di Biologia dei Leucociti
PUBBLICAZIONI SELEZIONATE
-
Fra AM, Locati M, Otero K, Sironi M, Signorelli P, Massardi ML, Gobbi M, Vecchi A, Sozzani S,
Mantovani A. Cutting Edge: Scavenging of inflammatory CC chemokines by the promiscuous putatively
silent chemokine receptor D6. Journal of Immunology, 170:2279-2282, 2003.
-
Di Liberto D, Locati M, Cacciamo N, Vecchi A, Meraviglia S, Dieli F, Mantovani A. Role of the
chemokine decoy receptor D6 in balancing inflammation, immune activation and antimicrobial
resistance in Mycobacterium tuberculosis infection. Journal of Experimental Medicine, in press,
2008.
-
Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini
F, Doni A, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Vecchi A,
Tedesco F, Lira SA, Locati M, Mantovani A. Protection against inflammation- and autoantibody-caused
fetal loss by the chemokine decoy receptor D6.
Proceedings of the National Academy of Sciences of U.S.A.,104:2319-2324, 2007.
-
Galliera E, Jala VR, Trent JO, Bonecchi R, Signorelli P, Lefkowitz RJ, Mantovani A, Locati M,
Haribabu B.
-Arrestin dependent constitutive internalisation of the chemokine decoy receptor D6.
Journal of Biological Chemistry, 279: 25590-25597, 2004.
-
Bonecchi R, Borroni EM, Anselmo A, Doni A, Savino B, Mirolo M, Fabbri M, Jala VJ, Haribabu B,
Mantovani A, Locati M. Regulation of D6 chemokine scavenging activity by ligand and rab11-dependent
surface upregulation. Blood, in press, 2008.
-
Mantovani A, Bonecchi R, Locati M. Tuning inflammation and immunity by chemokine
sequestration: decoys and more. Nature Reviews in Immunology, 12:907-918, 2006.
-
Martinez FO, Gordon S, Locati M, Mantovani A. Transcriptional profiling of the human
monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene
expression. Journal of Immunology, 177:7303-7311, 2006.
-
Mantovani A, Sica A, Locati M. Macrophage polarization comes of age. Immunity, 23:344-346,
2005.
-
Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in
diverse forms of macrophage activation and polarization. Trends in Immunology, 25: 677-686,
2004.
-
Scotton CJ, Martinez FO, Smelt MJ, Sironi M, Locati M, Mantovani A, Sozzani S.
Transcriptional profiling reveals complex regulation of the monocyte IL-1 system by IL-13. Journal
of Immunology, 174: 834-845, 2005.
-
Perrier P, Martinez FO, Locati M, Bianchi G, Nebuloni M, Vago G, Bazzoni F, Sozzani S,
Allavena P, Mantovani A. Distinct transcriptional programs activated by interleukin-10 with or
without lipopolysaccharide in dendritic cells: induction of the B cell-activating chemokine CXC
chemokine ligand 13. Journal of Immunology, 172:7031-7042, 2004.
-
Locati M, Deuschle U, Massardi ML, Martinez FO, Sironi M, Sozzani S, Bartfai T, Mantovani A.
Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and
lipopolysaccharide in human monocytes. Journal of Immunology 168:3557-3562, 2002.
-
Tamassia N, Le Migne V, Calzetti F, Donini M, Gasperini S, Ear T, Cloutier A, Martinez FO,
Fabbri M, Locati M, Mantovani A, McDonald P, Cassatella M. The MYD88-independent pathway is not
mobilized in human neutrophils stimulated via TLR4. Journal of Immunology, 178:7344-7356,
2007.
-
Bertini R, Allegretti M, Bizzarri C, Moriconi A, Locati M, Zampella G, Neve Cervellera M, Di
Cioccio V, Cesta MC, Galliera E , Martinez FO, Di Bitondo R, Troiani G, Sabbatini V, Anacardio R,
Cutrin JC, Cavalieri B, Mainiero F, Strippoli R, Villa P, Di Girolamo M, Martin F, Gentile M,
Santoni A, Corda D, Ghezzi P, Poli G, Mantovani A, Colotta F. Noncompetitive allosteric inhibitors
of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.
Proceedings of the National Academy of Sciences USA,101: 11791-11796, 2004.
-
Allegretti M, Bertini R, Bizzarri C, Beccari A, Mantovani A, Locati M. Allosteric inhibitors
of chemoattractant receptors.
Opportunities and pitfalls. Trends in Pharmacological Sciences, in press, 2008.
|
|
|
Istituto Clinico Humanitas